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Test Code ALDRQ Aldosterone, 24-Hour Urine

Specimen Required

1.5 mL random urine collected in a sterile, preservative-free, leakproof container OR 24-hour urine collected in a 24-hour urine container w/10 g Boric acid

Specimen Minimum Volume

0.8 mL

Specimen Stability

Room temperature: 7 days Refrigerated: 28 days Frozen: 21 days

Rejection Due To

Urine collected with HCl

Day(s) and Time(s) Performed

Set up: Sun, Tues; Report available: 4-10 days

Method Name

Extraction • Liquid Chromatography/Tandem Mass Spectrometry • Hydrolysis

Collection Container / Tube

Preferred: Sterile, preservative free container
Other Acceptable Container: 24 Hour Urine container w/10g Boric Acid

Transport / Storage Conditions

Room temperature

Special Instructions

Record 24-hour urine volume on test request form and urine vial. Refrigerate during and after collection. Reference ranges do not apply to random urine samples.

Reference Values

Aldosterone, 24-Hour Urine
Random sodium diet

 Age (mcg/24 hours) 
 2-7 years: 5.7 or less 
8-11 years:  10.2 or less 
12-16 years:  15.6 or less 
 Adults: 2.3-21.0 
 Post Florinef™ or IV saline supression
 5 mcg/24 hours or less
Creatinine, 24 Hour Urine
 Age  (g/24 h)
<3 years:  Not established
 3-8 years: 0.10-0.80
 9-12 years: 0.20-1.40
13-17 years: 0.40-1.90
>17 years: 0.50-2.15 

CPT Codes


Clinical Reference

Aldosterone is a hormone produced by the adrenal glands. Patients with primary hyperaldosteronism exhibit hypokalemia, hypertension, and low direct renin concentrations.