Sign in →

Test Code ALPRA Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Specimen Required

1.8 mL plasma

Specimen Minimum Volume

0.8 mL

Specimen Stability

Room temperature: 24 hours Refrigerated: 24 hours Frozen: 28 days

Rejection Due To

Plasma separator tube (PST)

Day(s) and Time(s) Performed

Set up: Sun-Fri nights; Report available: 4-6 days

Method Name

Chromatography/Mass Spectrometry

Includes

Aldosterone, LC/MS and Plasma Renin Activity, LC/MS/MS

Collection Container / Tube

Preferred: EDTA (lavendar tube)
Other Acceptable Container: None

Transport Container

Plastic screw-cap vial

Transport / Storage Conditions

Frozen

Reference Values

Aldosterone

Adult  
Upright 8:00-10:00 A.M. ≤28 ng/dL
Upright 4:00-6:00 P.M. ≤21 ng/dL
Supine 8:00-10:00 A.M. 3-16 ng/dL
Pediatric  
1-12 Months 2-70 ng/dL
1-4 Years 2-37 ng/dL
5-9 Years ≤9 ng/dL
10-13 Years ≤21 ng/dL
14-17 Years ≤35 ng/dL
Infants  
Premature (31-35 Weeks) ≤144 ng/dL
Term ≤217 ng/dL
Tanner Stages  
II-III Males 1-13 ng/dL
II-III Females 2-20 ng/dL
IV-V Males 3-14 ng/dL
IV-V Females 4-32 ng/dL

Plasma Renin Activity 0.25-5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9-28.9 Ratio

CPT Codes

82088, 84244

Clinical Reference

The Aldosterone-renin ratio is used to screen for primary aldosteronism.