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Test Code ATOCO Vitamin E, Serum

Reporting Name

Vitamin E, S

Useful For

Evaluation of individuals with motor and sensory neuropathies

 

Monitoring vitamin E status of premature infants requiring oxygenation

 

Evaluation of persons with intestinal malabsorption of lipids

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Patient Preparation: Fasting overnight (12-14 hours) (infants-draw prior to next feeding)

Supplies: Amber Frosted Tube, 5 mL (T192)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Amber vial

Specimen Volume: 0.5 mL

Collection Instructions: Within 24 hours of collection, aliquot specimen into amber vial to protect from light.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 44 days LIGHT PROTECTED
  Frozen  44 days LIGHT PROTECTED
  Ambient  7 days LIGHT PROTECTED

Reference Values

0-17 years: 3.8-18.4 mg/L

≥18 years: 5.5-17.0 mg/L

Day(s) and Time(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84446

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VITE Vitamin E, S 1823-4

 

Result ID Test Result Name Result LOINC Value
2350 A-Tocopherol, Vitamin E 1823-4

Clinical Reference

1. Ball GFM: Vitamins: Their role in the human body. Oxford, Blackwell Publishing. 2004:234-255

2. Traber MG: Vitamin E. In: Shils ME, Shike M, Ross AC, et al. Modern Nutrition in Health and Disease.10th ed. Lippincott Williams and Wilkins; 2006:434-441

3. Roberts NB, Taylor A, Sodi R: Vitamins and trace elements. In: Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:chap37

Method Description

Deuterated vitamin E (d[6]-alpha-tocopherol) is added to serum as an internal standard. Vitamin E (alpha-tocopherol) and the deuterated internal standard are extracted from the specimens and analyzed by liquid chromatography-tandem mass spectrometry.(Unpublished Mayo method)

Analytic Time

2 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.

Secondary ID

42358