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HelpTest Code ATOCO Vitamin E, Serum
Reporting Name
Vitamin E, SUseful For
Evaluation of individuals with motor and sensory neuropathies
Monitoring vitamin E status of premature infants requiring oxygenation
Evaluation of persons with intestinal malabsorption of lipids
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumShipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Patient Preparation: Fasting overnight (12-14 hours) (infants-draw prior to next feeding)
Supplies: Amber Frosted Tube, 5 mL (T192)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Amber vial
Specimen Volume: 0.5 mL
Collection Instructions: Within 24 hours of collection, aliquot specimen into amber vial to protect from light.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 44 days | LIGHT PROTECTED |
| Frozen | 44 days | LIGHT PROTECTED | |
| Ambient | 7 days | LIGHT PROTECTED |
Reference Values
0-17 years: 3.8-18.4 mg/L
≥18 years: 5.5-17.0 mg/L
Day(s) and Time(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
84446
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| VITE | Vitamin E, S | 1823-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 2350 | A-Tocopherol, Vitamin E | 1823-4 |
Clinical Reference
1. Ball GFM: Vitamins: Their role in the human body. Oxford, Blackwell Publishing. 2004:234-255
2. Traber MG: Vitamin E. In: Shils ME, Shike M, Ross AC, et al. Modern Nutrition in Health and Disease.10th ed. Lippincott Williams and Wilkins; 2006:434-441
3. Roberts NB, Taylor A, Sodi R: Vitamins and trace elements. In: Rifai N, Horvath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018:chap37
Method Description
Deuterated vitamin E (d[6]-alpha-tocopherol) is added to serum as an internal standard. Vitamin E (alpha-tocopherol) and the deuterated internal standard are extracted from the specimens and analyzed by liquid chromatography-tandem mass spectrometry.(Unpublished Mayo method)
Analytic Time
2 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.