Test Code CRPHS C-Reactive Protein, High Sensitivity
Additional Codes
Epic: LAB2233
Specimen Required
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Green top (Lithium heparin)
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions: Centrifuge and separate cells after clot formation and within 4 hours of collection.
Additional Information: Specimens from patients receiving anticoagulant or thrombolytic therapy may take longer to complete their clotting processes. Fibrin clots may form in these sera and the clots could cause erroneous test results.
Specimen Minimum Volume
0.25 mL
Specimen Stability
Room temperature: 15 days
Refrigerated: 2 months
Frozen: 3 years
Reference Range
≤ 0.5 mg/dL
Rejection Due To
Unlabeled, mislabeled, wrong tube type, hemolyzed, visually lipemic, QNS, exceeds specimen stability requirements.
Report Available
Same day
Clinical Significance
C-reactive protein is an acute phase protein whose concentration rises non-specifically in response to inflammation. CRP is seen to increase as a result of the inflammatory process, most notably in response to pneumococcal (bacterial) infection, histolytic disease, and a variety of other disease states. CRP is used as a marker or general diagnostic indicator of infections and inflammation, in addition to serving as a monitor of patient response to pharmacological therapy and surgery.
Method Name
Turbidimetric/Immunoturbidimetric
Limitations
CRP is not a substitute for traditional cardiovascular risk factors.
Acute coronary syndrome management should not depend on CRP measurements.
Patients with persistently unexplained CRP levels above 1.0 mg/dL should be evaluated for noncardiovascular etiologies.
LOINC
30522-7
Day(s) Performed
Daily