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Test Code F5L Factor V (Leiden) Mutation Analysis

Additional Codes

Epic: LAB346

Specimen Required

Specimen Type: Whole Blood EDTA

Collection Container/Type

Preferred: Lavedner top (EDTA)

Acceptable: Dark Blue top (EDTA), Green top (Sodium Heparin), Green top (Lithium Heparin), Yellow top (ACD solution A or B).

Specimen Volume: 5 mL

Additional Information:

  • Extracted DNA: Please call 1-866-GENE-INFO for additional information.

Specimen Minimum Volume

3 mL

Specimen Stability

Room temperature: 8 days
Refrigerated: 8 days
Frozen: 30 days

Clinical Significance

Factor V (Leiden) Mutation is a point mutation that causes resistance of Factor V protein degradation by activated protein C (APC). This mutation is associated with increased risk of venous thrombosis.

Reference Range

See laboratory report

Day(s) and Time(s) Performed


Report Available

4-5 days

Method Name

Polymerase Chain Reaction and Detection

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Performing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Hwy
San Juan Capistrano, CA 92675-2042