Test Code GENTP Gentamicin, Peak
Additional Codes
Epic: LAB28
Specimen Required
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions:
- Specimens should be drawn 30 minutes after a 30-minute IV infusion.
- Centrifuge and separate cells after clot formation and within 4 hours of collection.
Additional Information: Provide date and time of last dose.
Specimen Minimum Volume
0.2 mL
Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: >7 days
Reference Range
Theraputic values:
4.0 - 12.0 μg/mL
Rejection Due To
Unlabeled, mislabeled, wrong tube type, QNS, severely (grossly) hemolyzed samples, and any sample from which the lipid layer has not been removed.
Report Available
Same day
Clinical Significance
Gentamicin is an aminoglycoside antibiotic which exhibits high potency and a broad spectrum bacterial action against both gram-negative and gram-positive organisms. It exhibits a narrow therapeutic index which makes its use hazardous, especially in patients with impaired renal function. In addition, the dose-serum level profile curve of gentamicin is unpredictable, both in terms of peak-serum levels and elimination half-life from plasma. Gentamicin is used in the treatment of serious infections involving aminoglycoside-sensitive organisms. Monitoring gentamicin concentration in serum or plasma, along with careful clinical assessment, is the most effective means of ensuring adequate therapy.
Method Name
Chemiluminescent Microparticle Immunoassay (CMIA)
LOINC
3663-2
Day(s) Performed
Daily