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HelpTest Code GGT Gamma-Glutamyltransferase (GGT)
Additional Codes
Epic: LAB2298
Specimen Required
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Green top (Lithium Heparin)
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions: Centrifuge and separate cells after clot formation and within 1 hour of collection.
Specimen Minimum Volume
0.25 mL
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 1 year
Reference Range
Males
11 - 88 U/L
Female
10 - 70 U/L
Rejection Due To
Unlabeled, mislabeled, wrong tube type, QNS, hemolyzed.
Report Available
Same day
Clinical Significance
Renal tissue has the highest level of GGT, but is elevated in many forms of liver disease. GGT is elevated earlier and is more pronounced in obstructive jaundice and metastatic jaundice. It may reach 5 to 30 times normal levels in intra- or post hepatic biliary obstruction. GGT is also sensitive to alcohol use.
Method Name
L-gamma-glutamyl-3-carboxy-4-nitroanalide Substrate
Limitations
Bilirubin and Hemolysis can decrease GGT results by as much as 12-17%. Intralipid can increase GGT results by as much as 3%.
LOINC
2324-2
Day(s) Performed
Daily