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Test Code HAVG Hepatitis A IgG Antibody

Additional Codes

Epic: LAB12911

Specimen Required

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Centrifuge and separate cells after clot formation and within 4 hours of collection. 

Specimen Minimum Volume

0.5 mL

Specimen Stability

Room temperature: 4 days

Refrigerated: 8 days

Frozen: >8 days

Clinical Significance

Transmission of the Hepatitis A virus is via the fecal-oral route, and infection occurs mainly due to contaminated food or poor sanitary conditions.  The virus replicates in the liver and is shed in the stool.  Incubation period ranges from 15-40 days.  Symptoms last approximately 2 weeks and include hepatomegaly, jaundice, dark urine, fatigue, and gastrointestinal disturbances.  At the onset of symptoms, antibody to HAV is detectable, largely compromised of IgM subclass.  HAV IgM is detectable for 3-6 months, but HAV IgG can persist indefinitely.  The anti-HAVG assay is most useful as an aid in the diagnosis of previous hepatitis A infection or in the identification of HAV-susceptible individuals for vaccination.

Reference Range

Non-reactive

Rejection Due To

Unlabeled, mislabeled, wrong tube type, hemolyzed, QNS, exceeds specimen/stability requirements.

Day(s) and Time(s) Performed

Daily

Report Available

Same day

Method Name

Chemiluminescent microparticle immunoassay

LOINC

40724-7