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Test Code HAVM Hepatitis A IgM Antibody

Additional Codes

Epic: LAB798

Specimen Required

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Centrifuge and separate cells after clot formation and within 4 hours of collection. 

Specimen Minimum Volume

0.5 mL

Specimen Stability

Room temperature: Not defined

Refrigerated: 7 days

Frozen: > 7 days

Clinical Significance

    Transmission of the Hepatitis A virus is via the fecal-oral route, and infection occurs mainly due to contaminated food or poor sanitary conditions.  The virus replicates in the liver and is shed in the stool.  Incubation period ranges from 15-40 days.  Symptoms last approximately 2 weeks and include hepatomegaly, jaundice, dark urine, fatigue, and gastrointestinal disturbances.  At the onset of symptoms, antibodies to HAV are detectable, largely compromised of IgM subclass.  HAV IgM is detectable for 3-6 months, and then subsides.
The presence of HAV IgM indicates ongoing or recent infection and is the most useful serological marker for distinguishing acute hepatitis A virus infection.
 

Reference Range

See laboratory report

Rejection Due To

Unlabeled, mislabeled, wrong tube type, hemolyzed, QNS, exceeds specimen/stability requirements.

Day(s) and Time(s) Performed

Daily

Report Available

Same day

Method Name

Chemiluminescent microparticle immunoassay

LOINC

22314-9