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HelpTest Code HAVM Hepatitis A IgM Antibody
Additional Codes
Epic: LAB798
Specimen Required
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions: Centrifuge and separate cells after clot formation and within 4 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability
Room temperature: Not defined
Refrigerated: 7 days
Frozen: > 7 days
Clinical Significance
Transmission of the Hepatitis A virus is via
the fecal-oral route, and infection occurs mainly due to
contaminated food or poor sanitary conditions. The virus
replicates in the liver and is shed in the stool. Incubation
period ranges from 15-40 days. Symptoms last approximately 2
weeks and include hepatomegaly, jaundice, dark urine, fatigue, and
gastrointestinal disturbances. At the onset of symptoms,
antibodies to HAV are detectable, largely compromised of IgM
subclass. HAV IgM is detectable for 3-6 months, and then
subsides.
The presence of HAV IgM indicates ongoing or recent infection and
is the most useful serological marker for distinguishing acute
hepatitis A virus infection.
Reference Range
See laboratory report
Rejection Due To
Unlabeled, mislabeled, wrong tube type, hemolyzed, QNS, exceeds specimen/stability requirements.
Day(s) and Time(s) Performed
Daily
Report Available
Same day
Method Name
Chemiluminescent microparticle immunoassay
LOINC
22314-9