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Test Code HGPPR Hemoglobinopathy Profile

Important Note

Test requires both whole blood and plasma specimens.

Additional Codes

Epic: LAB3158

Quest: 8547

Specimen Required

Patient Preparation: 

Specimen Type: Whole blood EDTA AND Plasma Sodium Heparin

Collection Container/Type: Lavender top (EDTA) AND Green top (Sodium heparin)

Submission Container/Tube: Lavender top (EDTA) tube AND Plastic vial

Specimen Volume: 5 mL whole blood & 1 mL plasma

Collection Instructions: 

  1. Centrifuge sodium heparin tube within 1 hour of collection.  Transfer plasma to a plastic vial.
  2. Send lavender samples in original collection tube, do not aliquot.

Additional Information:

  1. If only normal Hemoglobins are detected, the results will be reported within 24 hours.
    However, if any abnormal Hemoglobins are present that require additional testing, turnaround time may take as long as 5 days.
    Specimens for Hemoglobin by HPLC are stable for 7 days at refrigerator temperature. However, if Hemogram is needed for accurate interpretation, the Hemogram portion is only stable for 3 days from the time of collection at refrigerator temperature.

Specimen Minimum Volume

4 mL Whole Blood & 0.2 mL plasma

Specimen Stability

Room temperature: 7 days

Refrigerated: 7 days

Frozen: Unacceptable

Reference Range

See laboratory report

Report Available

1 - 3 days

Method Name

High Performance Liquid Chromatography (HPLC) Colorimetry (C) Electrophoresis

High Performance Liquid Chromatography


Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153


Hemoglobinopathy Evaluation w/o Hemogram; Hemoglobin, Free, Plasma (Hemoglobin A; Hemoglobin F; Hemoglobin A2 (Quant); Hemoglobin A2 Prime; Hemoglobin S; Hemoglobin C; Hemoglobin D; Hemoglobin G; Hemoglobin Lepore; Hemoglobin E; Hemoglobin O-Arab; Hemoglobin Barts; Variant Hemoglobin; Sickle Cell Screen; Hemoglobin F, Differential Staining)

Day(s) Performed

Hemoglobin A2, Quantitative: Tuesday - Sunday

Hemoglobin, Free, Plasma: Tuesday - Saturday PM

Hemoglobinopathy Evaluation: Monday - Friday