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HelpTest Code HIPAB Heparin-Induced Platelet Antibody
Specimen Required
1 mL random serum
Specimen Minimum Volume
0.5 mL
Specimen Stability
Room temperature: Unacceptable Refrigerated: Unacceptable Frozen: 6 months
Rejection Due To
Received room temperature • Gross hemolysis • Lipemia • Icteric • Serum separator tube (SST®)
Method Name
Immunoassay (IA)
Limitations
When heparin is stopped, antibody that may have been present disappears within weeks to months.
Collection Container / Tube
Preferred: Red Top Tube (no gel)
Other Acceptable Container: 3.2 % sodium citrate (light-blue)
Transport Container
Plastic screw-cap vial
Transport / Storage Conditions
Frozen
Special Instructions
Serum: Centrifuge red top tube 15 minutes at
approximately 1500 g as soon as possible after clotting.
Plasma: Centrifuge blue top tube 20 minutes at
approximately 2500 g. Remove plasma from the cells as soon as
possible.
Reference Values
| Heparin-Induced Platelet Antibody | Negative |
| Patient O.D. | ≤0.300 OD Units |
Day(s) Performed
Set up: Daily; Report available: 1 day
CPT Codes
86022
Clinical Reference
Heparin can induce thrombocytopenia, a decreased platelet count, due to antibody stimulation. False positive results may be due to immune complexes. False negative results may be due to low titer, low avidity antibodies.