Test Code HIPAB Heparin-Induced Platelet Antibody
Specimen Required
1 mL random serum
Specimen Minimum Volume
0.5 mL
Specimen Stability
Room temperature: Unacceptable Refrigerated: Unacceptable Frozen: 6 months
Rejection Due To
Received room temperature • Gross hemolysis • Lipemia • Icteric • Serum separator tube (SST®)
Day(s) and Time(s) Performed
Set up: Daily; Report available: 1 day
Method Name
Immunoassay (IA)
Collection Container / Tube
Preferred: Red Top Tube (no gel)
Other Acceptable Container: 3.2 % sodium citrate (light-blue)
Transport Container
Plastic screw-cap vial
Transport / Storage Conditions
Frozen
Special Instructions
Serum: Centrifuge red top tube 15 minutes at
approximately 1500 g as soon as possible after clotting.
Plasma: Centrifuge blue top tube 20 minutes at
approximately 2500 g. Remove plasma from the cells as soon as
possible.
Reference Values
Heparin-Induced Platelet Antibody | Negative |
Patient O.D. | ≤0.300 OD Units |
CPT Codes
86022
Clinical Reference
Heparin can induce thrombocytopenia, a decreased platelet count, due to antibody stimulation. False positive results may be due to immune complexes. False negative results may be due to low titer, low avidity antibodies.
Limitations
When heparin is stopped, antibody that may have been present disappears within weeks to months.