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Test Code HIPAB Heparin-Induced Platelet Antibody

Specimen Required

1 mL random serum

Specimen Minimum Volume

0.5 mL

Specimen Stability

Room temperature: Unacceptable Refrigerated: Unacceptable Frozen: 6 months

Rejection Due To

Received room temperature • Gross hemolysis • Lipemia • Icteric • Serum separator tube (SST®)

Day(s) and Time(s) Performed

Set up: Daily; Report available: 1 day

Method Name

Immunoassay (IA)

Collection Container / Tube

Preferred: Red Top Tube (no gel)
Other Acceptable Container: 3.2 % sodium citrate (light-blue)

Transport Container

Plastic screw-cap vial

Transport / Storage Conditions


Special Instructions

Serum: Centrifuge red top tube 15 minutes at approximately 1500 g as soon as possible after clotting.
Plasma: Centrifuge blue top tube 20 minutes at approximately 2500 g. Remove plasma from the cells as soon as possible.

Reference Values

Heparin-Induced Platelet Antibody Negative
Patient O.D. ≤0.300 OD Units

CPT Codes


Clinical Reference

Heparin can induce thrombocytopenia, a decreased platelet count, due to antibody stimulation. False positive results may be due to immune complexes. False negative results may be due to low titer, low avidity antibodies.


When heparin is stopped, antibody that may have been present disappears within weeks to months.