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Test Code HPAGS Helicobacter pylori Antigen, EIA, Stool

Additional Codes

Epic:

Quest: 34838

Specimen Required

Patient Preparation: 

For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained.

To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days post therapy is indicative of treatment failure.
This test is cleared for use with specimens from pediatric patients.

Specimen Type: Unpreserved Stool

Collection Container/Type: Sterile container

Submission Container/Tube: Sterile container, no preservative

Specimen Volume: 0.5 mL / 0.5 g / 20 mm diameter

Collection Instructions: 

  1. Collect 0.5 mL of semisolid stool or 20 mm diameter of solid stool and transfer to a properly labeled sterile, plastic, leakproof container.
  2. Do not place stool in preservative, transport medium, or swab. Watery, diarrheal stool is not acceptable.

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: 30 days

Reference Range

See Laboratory Report

Rejection Due To

Watery, diarrheal stool • Stool in preservative, transport media or swab • Received room temperature

Report Available

1-4 days

Clinical Significance

Colonization with H. pylori is associated with increased risk of patients developing gastritis, peptic ulcer disease, and gastric adenocarcinoma. Stool antigen testing provides a sensitive measure of infection including during and after treatment.

Method Name

Immunoassay (IA)

CPT Code(s)

87338

Limitations

There may be possible false-negative results associated with recent PPI use.

Aliases

H. pylori Antigen, H. pylori Stool Antigen

Day(s) Performed

Daily