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Test Code IBDDP Inflammatory Bowel Disease Differentiation Panel

Additional Codes

Epic: LAB12264

Specimen Required

Patient Preparation: 

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Specimen Minimum Volume

1.4 mL

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days

Clinical Significance

These tests are intended to aid in the diagnosis of Crohn's Disease. A positive P-ANCA aids in the differentiation of patients with ulcerative colitis.

Reference Range

ANCA Screen Negative
  P-ANCA Titer <1:20
  C-ANCA Titer <1:20
  Atypical P-ANCA Titer <1:20

Myeloperoxidase Antibody

<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Proteinase-3 Antibody

<1.0 AI No antibody detected
≥1.0 AI Antibody detected

Saccharomyces cerevisiae Ab (IgG)

≤20.0 U Negative
20.1-29.9 U Equivocal
≥30.0 U Positive

Saccharomyces cerevisiae Ab (IgA)

≤20.0 U Negative
20.1-24.9 U Equivocal
≥25.0 U Positive

Rejection Due To

Gross hemolysis • Lipemic specimens

Day(s) and Time(s) Performed

Monday - Saturday, P.M.

Report Available

3-5 days

Method Name

Immunoassay (IA)


8796 Myeloperoxidase Antibody
10294 Saccharomyces cerevisiae Antibody (ASCA) (IgG)
10295 Saccharomyces cerevisiae Antibody (ASCA) (IgA)
34151 Proteinase-3 Antibody
70171 ANCA Screen with Reflex to ANCA Titer

Testing Algorithm

If ANCA Screen is positive, then C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86021 for each titer performed).


86021 (x3), 86671 (x2)


IBD Panel

Performing Laboratory

Quest Diagnostics

Chantilly, VA