Test Code IL28B AccuType(TM) IL28B
Specimen Required
5 mL whole blood
Specimen Minimum Volume
2 mL
Specimen Stability
Whole blood
Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable
Buccal swab
Room temperature: 14 days
Refrigerated: Unacceptable
Frozen: Unacceptable
Rejection Due To
Received frozen • Buccal swab received refrigerated • Incorrect collection device • Liquid has leaked from container/no liquid present
Report Available
Set up: Daily night; Report available: 3 days
Method Name
Real-Time Polymerase Chain Reaction
Collection Container / Tube
Preferred: EDTA (lavendar-top)
tube.
Other Acceptable Container: ACD solution
A or B (yellow-top) tube Buccal swab collected in: DNA Genotek Oracollect Kit, or Celera DNA Collection Kit (follow collection kit
instructions)
Transport / Storage Conditions
Room temperature
Special Instructions
Do not freeze whole blood.
Buccal Swab: Use only Celera/Copan
DNA Collection Kit (Celera part # is
5002737) or DNA Genotek OraCollect Kit
(OC-100). Follow collection kit instructions.
Reference Values
See Laboratory Report
Day(s) Performed
Set up: Daily night; Report available: 3 days
CPT Codes
81283
This test is for non-New York patient testing. For New York
testing, please see Test Code 90252.
Clinical Reference
The C polymorphism in rs12979860 is strongly associated with a two fold greater sustained virological response in European, African American, and Hispanic populations. Knowledge of the host genotype of patients infected with HCV will aid in the clinical decision to initiate treatment with PegIFN and RBV (a 48 week course of interferon and ribavirin which has limited efficacy and is often poorly tolerated due to side effects that prevent patients from finishing treatment).
Patient Preparation
Do not eat immediately prior to sample collection. If patient has eaten recently, rinse mouth with plain water.