Home
HelpTest Code KLLCF Kappa/Lambda Light Chains, Free with Ratio Reflex to Immunofixation, Serum
Additional Codes
Epic: LAB3222
Quest: 15122
Testing Algorithm
If Kappa/Lambda, Free is <0.26 or >1.65, Immunofixation will be performed at an additional charge (CPT code(s): 86334).
Specimen Required
Specimen Type: Serum
Collection Container/Type
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Specimen Minimum Volume
1 mL
Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Reference Range
| Kappa Light Chain, Free, Serum | 3.3-19.4 mg/L |
| Lambda Light Chain, Free, Serum | 5.7-26.3 mg/L |
| Kappa/Lambda Light Chains Free with Ratio, Serum | 0.26-1.65 |
Rejection Due To
Gross hemolysis • Grossly lipemic • Microbially contaminated serum • Specimens containing heavy visible particulate
Day(s) and Time(s) Performed
Mon-Fri
Report Available
2-7 days
Clinical Significance
Measurement of the amounts of the different light chain types aids in the diagnosis and monitoring of multiple myeloma, lymphocytic neoplasms, Waldenstrom's macroglobulinemia, and connective tissue diseases, such as systemic lupus erythematosus.
Method Name
Immunoturbidimetric
CPT Code(s)
83521 (x2)
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Includes
549: Immunofixation, Serum
11234: Kappa/Lambda Light Chains, Free with Ratio, Serum
Aliases
Light Chains