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HelpTest Code KLLCF Kappa/Lambda Light Chains, Free with Ratio and Reflex to Immunofixation
Specimen Required
2 mL serum
Specimen Minimum Volume
1 mL
Specimen Stability
Room temperature: 72 hours Refrigerated: 7 days Frozen: 30 days
Rejection Due To
Gross hemolysis • Grossly lipemic • Microbially contaminated serum • Specimens containing heavy visible particulate
Day(s) and Time(s) Performed
Set up: Mon-Fri; Report available: Next day
Method Name
Immunoturbidimetric
Includes
If Kappa/Lambda, Free is <0.26 or >1.65, Immunofixation will be performed at an additional charge (CPT code(s): 86334).
Collection Container / Tube
Preferred: Gold SST Tube
Other Acceptable Container: None
Transport Container
Plastic screw-cap vial
Transport / Storage Conditions
Room temperature
Reference Values
| Kappa Light Chain, Free, Serum | 3.3-19.4 mg/L |
| Lambda Light Chain, Free, Serum | 5.7-26.3 mg/L |
| Kappa/Lambda Light Chains Free with Ratio, Serum | 0.26-1.65 |
CPT Codes
83520 (x2)
Clinical Reference
Measurement of the amounts of the different light chain types aids in the diagnosis and monitoring of multiple myeloma, lymphocytic neoplasms, Waldenstrom’s macroglobulinemia, and connective tissue diseases, such as systemic lupus erythematosus.