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Test Code LACTA Lactic Acid

Important Note

Samples should be obtained without the use of a tourniquet.

Additional Codes

Epic: LAB95

Specimen Required

Specimen Type: Plasma NaFl-KOx

Collection Container/Type: Grey top (potassium oxalate/sodium fluoride)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: 

  1. Draw specimen without a tourniquet
  2. Centrifuge and separate plasma immediately.
  3. Whole blood samples are not acceptable. 

Specimen Minimum Volume

2 mL

Specimen Stability

Room temperature: Unaccpetable

Refrigerated: 3 days

Frozen: 3 days

Clinical Significance

Lactate is a byproduct of glucose metabolism.  The intermediary step in this pathway in the conversion of pyruvate to lactate by lactate dehydrogenase.  Lactate is generated in red blood cells, muscle, the brain and the gut.  Under normal circumstances, there is a small amount of lactate in the blood.  Type A lactic acidosis is caused by insufficient oxygenation of tissues.  In the decreased oxygen environment, anaerobic metabolism results.  Causes include circulatory failure, trauma, and profound anemia most commonly associated with strenuous exertion and exercise.  Type B lactic acidosis is due to overproduction of lactate or inadequate oxygen utilization most commonly associated with malignancies, diabetes, severe infection and several drugs.

Reference Range

0.2 - 2 mmol/L

Rejection Due To

Over or under filled, hemolysis, unlabeled and wrong tube type.

Day(s) and Time(s) Performed

Monday - Sunday

Report Available

1 day

Method Name

Lactic Acid to Pyruvate