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Test Code LDPNL Lactate Dehydrogenase (LD) Isoenzyme Panel

Additional Codes

Epic: LAB3231

Quest: 4411

Specimen Required

Specimen Type: Serum

Collection Container/Type: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: 

  1. Centrifuge serum specimens within 1 hour of collection.
  2. Transfer serum to a clean, plastic, screw-capped vial(s).
  3. transport at room temperature to the laboratory. Do not refrigerate or freeze the specimens.

Additional Information:

  • Specimens cannot be shared, and no other tests should be ordered with Lactate Dehydrogenase Isoenzymes.

Specimen Minimum Volume

1 mL

Specimen Stability

Room temperature: 7 days

Refrigerated: Unacceptable

Frozen: Unacceptable

Reference Range

See Laboratory Report

Rejection Due To

Hemolysis • Received refrigerated • Received frozen

Day(s) and Time(s) Performed

Mon, Wed, Fri

Report Available

Same day

Clinical Significance

Lactate dehydrogenase (LD) is present in many different organs and tissues such as liver, heart, muscles, kidney, lungs and blood. The usual designation of isoenzymes is LD-I, LD-II, LD-III, LD-IV and LD-V. LD isoenzymes tissue specificity is derived from the fact that LD subunits are synthesized in well-defined ratios and could be used in investigating unexplained causes of Total LD elevations and detection of macro-LD. Do not use LD isoenzymes to detect myocardial injury.

Method Name

Electrophoresis • Spectrophotometry (SP)

CPT Code(s)

83615, 83625

Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153


LD Isoenzymes (LD1, LD2, LD3, LD4, LD5)

Lab Processing Instructions (Lab Use Only)

Do not share specimen with other testing.

Cannot be added on to specimens in lab.