Sign in →

Test Code LIPA Lipoprotein (a), Serum

Reporting Name

Lipoprotein (a), S

Useful For

Cardiovascular disease (CVD) risk refinement in patients with moderate or high risk based on conventional risk factors

 

This test is not recommended as a screening test in the healthy population.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation: Fasting-overnight (12-14 hours)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial. Send refrigerated.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  7 days

Reference Values

≤30 mg/dL

Values >30 mg/dL may suggest increased risk of coronary heart disease.

Day(s) and Time(s) Performed

Monday through Saturday; Continuously

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83695

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LIPA Lipoprotein (a), S 10835-7

 

Result ID Test Result Name Result LOINC Value
LIPA Lipoprotein (a), S 10835-7

Clinical Reference

1. Emerging Risk Factors Collaboration, Erqou S, Kaptoge S, et al: Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA. 2009 Jul 22;302(4):412-423

2. Lackner C, Cohen JC, Hobbs HH: Molecular definition of the extreme size polymorphism in apolipoprotein(a). Hum Mol Genet. 1993;2:933-940

3. Albers JJ, Slee A, O'Brien KD, et al: Relationship of apolipoproteins A-1 and B, and lipoprotein(a) to cardiovascular outcomes: the AIM-HIGH trial (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes). J Am Coll Cardiol. 2013 Oct 22;62(17):1575-1579

4. Erqou S, Thompson A, Di Angelantonio E, et al: Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants. J Am Coll Cardiol. 2010 May 11;55(19):2160-2167

Method Description

This test is a particle enhanced immunoturbidimetric assay. Human lipoprotein (a)(Lp[a]) agglutinates with the latex particles coated with anti-Lp(a) antibodies.(Package insert: Roche Lipoprotein (a) Gen.2 reagent. Roche Diagnostic Corp; V2.0 01/2015)

Analytic Time

Same day/1 day

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Method Name

Immunoturbidimetric Assay

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.