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HelpTest Code LKM Liver/Kidney Microsome Type 1 Antibodies, Serum
Reporting Name
Liver/Kidney Microsome Type 1 Ab, SUseful For
Evaluation of patients with liver disease of unknown etiology
Evaluation of patients with suspected autoimmune hepatitis
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.5 mL
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Reference Values
≤20.0 Units (negative)
20.1-24.9 Units (equivocal)
≥25.0 Units (positive)
Reference values apply to all ages.
Day(s) and Time(s) Performed
Monday, Wednesday, Friday
Test Classification
This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86376
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| LKM | Liver/Kidney Microsome Type 1 Ab, S | 32220-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| LKM | Liver/Kidney Microsome Type 1 Ab, S | 32220-6 |
Clinical Reference
1. Clinical Immunology Principles and Practice. Third edition. Edited by RR Rich, TA Fliesher, WT Shearer, et al: Philadelphia, PA, Mosby Elsevier, 2008
2. Czaja AJ, Homburger HA: Autoantibodies in liver disease. Gastroenterology. January 2001;120(1):239-249
Method Description
Enzyme-linked immunosorbent assay (ELISA) for the semi-quantitative detection of liver/kidney microsomal antibodies type 1 (LKM-1) antibodies in human serum.(Package insert: INOVA Diagnostics, Inc. San Diego, Revision 1, March 2000)
Analytic Time
1 dayReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Forms
If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.