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Test Code LKM Liver/Kidney Microsome Type 1 Antibodies, Serum

Reporting Name

Liver/Kidney Microsome Type 1 Ab, S

Useful For

Evaluation of patients with liver disease of unknown etiology

 

Evaluation of patients with suspected autoimmune hepatitis

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reference Values

≤20.0 Units (negative)

20.1-24.9 Units (equivocal)

≥25.0 Units (positive)

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday, Wednesday, Friday

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86376

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LKM Liver/Kidney Microsome Type 1 Ab, S 32220-6

 

Result ID Test Result Name Result LOINC Value
LKM Liver/Kidney Microsome Type 1 Ab, S 32220-6

Clinical Reference

1. Clinical Immunology Principles and Practice. Third edition. Edited by RR Rich, TA Fliesher, WT Shearer, et al: Philadelphia, PA, Mosby Elsevier, 2008

2. Czaja AJ, Homburger HA: Autoantibodies in liver disease. Gastroenterology. January 2001;120(1):239-249

Method Description

Enzyme-linked immunosorbent assay (ELISA) for the semi-quantitative detection of liver/kidney microsomal antibodies type 1 (LKM-1) antibodies in human serum.(Package insert: INOVA Diagnostics, Inc. San Diego, Revision 1, March 2000)

Analytic Time

1 day

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Client Test Request (T728) with the specimen.

Secondary ID

80387