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Mayo Clinic Laboratories

Test Code MARTP Mitochondrial Antibody Screen with Reflex to Titer

Specimen Required

0.5 mL serum

Specimen Minimum Volume

0.1 mL

Specimen Stability

Room temperature: 7 days Refrigerated: 14 days Frozen: 30 days

Rejection Due To

Gross hemolysis • Gross lipemia

Method Name

Immunoassay (IA)

Includes

If Mitochondrial Antibody Screen is positive, Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86256).

Collection Container / Tube

Preferred: Gold SST Tube
Other Acceptable Container: None

Transport Container

Plastic screw-cap vial

Transport / Storage Conditions

Room temperature

Reference Values

Negative

Day(s) Performed

Set up: Mon-Fri a.m.; Report available: Next day

CPT Codes

86255

Clinical Reference

A high Anti-Mitochondrial Antibody (AMA) titer supports the diagnosis of primary biliary cirrhosis (PBC). Low titers of AMA may be detected in other liver disorders, which include chronic active hepatitis and cryptogenic cirrhosis. Mitochondrial M2 Antibody has an even higher specificity for PBC.

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