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HelpTest Code PBDV Lead, Venous, with Demographics, Blood
Reporting Name
Lead, Venous, w/Demographics, BUseful For
Detecting lead toxicity in venous blood specimens
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Whole bloodSpecimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies:
-Metal Free B-D Tube (EDTA), 6 mL (T183)
-Metal Free (Lead only) EDTA Tube, 3mL (T615)
-If ordering the trace element blood collection tube from Becton Dickenson (BD), order catalog #368381
Container/Tube:
Preferred: Royal blue-top BD Vacutainer Plus with EDTA blood collection tube
Acceptable: Tan-top (lead only) BD Vacutainer Plus with EDTA blood collection tube
Specimen Volume: 2 mL
Collection Instructions:
1. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.
2. Send specimen in original tube.
Specimen Minimum Volume
0.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Special Instructions
Reference Values
All ages: <5.0 mcg/dL
Critical values
Pediatrics (≤15 years): ≥20.0 mcg/dL
Adults (≥16 years): ≥70.0 mcg/dL
Day(s) and Time(s) Performed
Monday through Friday; 5 p.m.
Saturday; 2 p.m.
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
83655
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PBDV | Lead, Venous, w/Demographics, B | 77307-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 65640 | Lead, Venous, B | 77307-7 |
| PTAD8 | Patient Street Address | 56799-0 |
| PTCI8 | Patient City | 68997-6 |
| PTST8 | Patient State | 46499-0 |
| PTZI8 | Patient Zip Code | 45401-7 |
| PTCN8 | Patient County | 87721-7 |
| PTPH8 | Patient Home Phone | 42077-8 |
| PTRA8 | Patient Race | 32624-9 |
| PTET8 | Patient Ethnicity | 69490-1 |
| PTOC8 | Patient Occupation | 11341-5 |
| PTEM8 | Patient Employer | 80427-8 |
| GDFN8 | Guardian First Name | 79183-0 |
| GDLN8 | Guardian Last Name | 79184-8 |
| MDOR8 | Health Care Provider Name | 52526-1 |
| MDAD8 | Health Care Provider Street Address | 74221-3 |
| MDCI8 | Health Care Provider City | 52531-1 |
| MDST8 | Health Care Provider State | 52532-9 |
| MDZI8 | Health Care Provider Zip Code | 87720-9 |
| MDPH8 | Health Care Provider Phone | 68340-9 |
| LABP8 | Submitting Laboratory Phone | 65651-2 |
Clinical Reference
1. CDC: National Report on Human Exposure to Environmental Chemicals. Updated Tables. Accessed: 01/2019. Available at: cdc.gov/exposurereport
2. Agency for Toxic Substances and Disease Registry: Toxological Profile for Lead. Accessed: 05/2019. Available at: www.atsdr.cdc.gov/ToxProfiles/tp13.pdf
3. de Burbure C, Buchet JP, Leroyer A, et al: Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels. Environ Health Perspect 2006;114:584-590
4. Kosnett MJ, Wedeen RP, Rothenberg SJ, et al: Recommendations for medical management of adult lead exposure. Environ Health Perspect 2007;115:463-471
5. Jusko T, Henderson C, Lanphear B, et al: Blood lead concentrations <10 mcg/dL and child intelligence at 6 years of age. Environ Health Perspect 2008;116:243-248
6. Nader R, Horwath AR, Wittwer CT: Toxic Elements. In Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Chapter 42. Sixth Edition. Elsevier. 2018 pp 907-910
Method Description
Lead (Pb) in whole blood is analyzed by inductively coupled plasma-mass spectrometry (ICP-MS) in standard mode using iridium (Ir) as an internal standard and using a salt matrix calibration.(Unpublished Mayo method)
Analytic Time
1 dayReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
| Clotted blood | Reject |
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Forms
1. Lead and Heavy Metals Reporting (T491) in Special Instructions
2. If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.
Secondary ID
113401Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PBBV | Lead, Venous, B | No | Yes |
| DEMO8 | Patient Demographics | No | Yes |