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Test Code RAPAM Sirolimus

Additional Codes

Epic: LAB875

Specimen Required

Specimen Type: Whole Blood (EDTA)

Collection Container/Type: Lavender top (EDTA)

Submission Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: 

  1. Samples should be drawn immediately before next dose.
  2. Do not centrifuge.
  3. Send sample in original collection container.

Specimen Minimum Volume

0.35 mL

Specimen Stability

Room temperature: Unacceptable

Refrigerated: 7 days

Frozen: 3 months (Tietz)

Reference Range

5.0 - 15.0 ng/mL

Rejection Due To

Unlabeled, mislabeled, wrong tube type, clotted, QNS, exceeds specimen/stability requirements.

Report Available

Same day/1 day

Method Name

Sirolimus is an immunosuppressive drug for renal transplant immunosuppressive therapy. Because of potential toxic effects associated with high trough levels of sirolimus, therapeutic drug monitoring of sirolimus immunosuppressive therapy has been recommended. Sirolimus is a macrocyclic lactone fermentation product of Streptomyces hygroscopicus, first discovered in the soil of Rapa Nui.




Day(s) Performed