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HelpTest Code RAPAM Sirolimus
Additional Codes
Epic: LAB875
Specimen Required
Specimen Type: Whole Blood (EDTA)
Collection Container/Type: Lavender top (EDTA)
Submission Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL
Collection Instructions:
- Samples should be drawn immediately before next dose.
- Do not centrifuge.
- Send sample in original collection container.
Specimen Minimum Volume
0.35 mL
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 3 months (Tietz)
Reference Range
5.0 - 15.0 ng/mL
Rejection Due To
Unlabeled, mislabeled, wrong tube type, clotted, QNS, exceeds specimen/stability requirements.
Day(s) and Time(s) Performed
Daily
Report Available
Same day/1 day
Method Name
Sirolimus is an immunosuppressive drug for renal transplant immunosuppressive therapy. Because of potential toxic effects associated with high trough levels of sirolimus, therapeutic drug monitoring of sirolimus immunosuppressive therapy has been recommended. Sirolimus is a macrocyclic lactone fermentation product of Streptomyces hygroscopicus, first discovered in the soil of Rapa Nui.
Aliases
Rapamune
Rapamycin