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Test Code SRA2 Serotonin Release Assay (SRA), Unfractionated Heparin

Additional Codes

Epic: LAB3365

Quest: 14627

Specimen Required

Specimen Type: Serum

Collection Container/Type

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Specimen Minimum Volume

0.4 mL

Specimen Stability

Room temperature: 24 hours
Refrigerated: 48 hours
Frozen: 6 months

Reference Range

See Laboratory Report

Rejection Due To

Received room temperature • Received refrigerated

Day(s) and Time(s) Performed

Sun-Fri a.m.

Report Available

1 day

Clinical Significance

Any patient with an unexplained fall in the platelet count of >40% during or after cessation of heparin therapy should be suspected of heparin-induced thrombocytopenia (HIT).

Method Name

Radiobinding 14C Serotonin Radiolabel

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

CPT Code(s)


Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153