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Test Code VB12B Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin)

Specimen Required

1 mL serum

Specimen Minimum Volume

0.2 mL

Specimen Stability

Room temperature: 4 days Refrigerated: 14 days Frozen: 30 days

Method Name

Radiobinding Assay

Collection Container / Tube

Preferred: Gold SST Tube
Other Acceptable Container: None

Transport Container

Plastic screw-cap vial

Transport / Storage Conditions

Refrigerated (cold packs)

Reference Values

Adults 650-1340 pg/mL

Day(s) Performed

Set up: Tues, Thurs, Sat afternoon; Report available: 1 day

CPT Codes


Clinical Reference

Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin), binds and transports vitamin B12 in the circulation. Increased concentrations are associated with patients with myeloproliferative disorders. Decreased concentrations are seen in individuals with megaloblastic anemia or Transcobalamin deficiency.