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Mayo Clinic Laboratories

Test Code VB12B Vitamin B12 Binding Capacity, Unsaturated (Transcobalamin)

Specimen Required

1 mL serum

Specimen Minimum Volume

0.2 mL

Specimen Stability

Room temperature: 4 days Refrigerated: 14 days Frozen: 30 days

Method Name

Radiobinding Assay

Collection Container / Tube

Preferred: Gold SST Tube
Other Acceptable Container: None

Transport Container

Plastic screw-cap vial

Transport / Storage Conditions

Refrigerated (cold packs)

Reference Values

Adults 650-1340 pg/mL

Day(s) Performed

Set up: Tues, Thurs, Sat afternoon; Report available: 1 day

CPT Codes

82608

Clinical Reference

Vitamin B₁₂ Binding Capacity, Unsaturated (Transcobalamin), binds and transports vitamin B₁₂ in the circulation. Increased concentrations are associated with patients with myeloproliferative disorders. Decreased concentrations are seen in individuals with megaloblastic anemia or Transcobalamin deficiency.

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