Sign in →

Test Code ZINCS Zinc, Serum

Additional Codes

Epic: LAB581

Mayo: ZNS

Reporting Name

Zinc, S

Useful For

Detecting zinc deficiency

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to interfere with most metals tests. If gadolinium-, iodine-, or barium-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.

Supplies:

-Metal Free B-D Tube (No Additive), 6 mL (T184)

-Metal Free Specimen Vial (T173)

Collection Container/Tube: 6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Submission Container/Tube: 7-mL Metal-free, screw-capped, polypropylene vial

Specimen Volume: 0.8 mL

Collection Instructions:

1. Allow the specimen to clot for 30 minutes after collection; then centrifuge the specimen to separate serum from the cellular fraction. Serum must be removed from cellular fraction within 4 hours of specimen collection. Avoid hemolysis.

2. Remove the stopper. Carefully pour specimen into a metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

3. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.


Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days METAL FREE
  Ambient  28 days METAL FREE
  Frozen  28 days METAL FREE

Reference Values

0-10 years: 0.60-1.20 mcg/mL

≥11 years: 0.66-1.10 mcg/mL

Day(s) and Time(s) Performed

Monday; 2 p.m.

Tuesday through Friday; 5 p.m.

Saturday; 2 p.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

84630

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ZNS Zinc, S 5763-8

 

Result ID Test Result Name Result LOINC Value
8620 Zinc, S 5763-8

Clinical Reference

1. Tucker SB, Schroeter AL, Brown PW Jr, McCall JT: Acquired zinc deficiency: cutaneous manifestations typical of acrodermatitis enteropathica. JAMA. 1976;235:2399-2402

2. Skelton JA, Havens PL, Werlin SL: Nutrient deficiencies in tube-fed children. Clin Pediatr (Phila). 2006;45(1):37-41

3. Zorbas YG, Kakuris KK, Neofitov IA, Afoninos NI: Zinc utilization in zinc-supplemented and-unsupplemented healthy subjects during and after prolonged hypokinesis. Tr Elem Electro. 2008;25:60-68

4. Rifai N, Horwath AR, Wittwer CT, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. Elsevier; 2018

Method Description

Zinc in serum is analyzed by inductively coupled plasma-mass spectrometry in dynamic reaction cell mode using  gallium as an internal standard and a salt matrix calibration.(Unpublished Mayo method)

Analytic Time

1 day

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Method Name

Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS)

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.